Researchers have successfully defined molecular subtypes of lymphoma from three separate dog breeds by comparing them to their human counterparts. Lymphoma, a group of blood cancers that develop in the lymphatic system, is the most common cancer in dogs and develops in over 550,000 humans a year.
A paper on the research was published by Ingegerd Elvers, et al. in Genome Research on September 16, 2015 and clearly illustrates the importance of translational research benefiting both global human and animal health. Senior author Dr. Jessica Alfoldi of the Broad Institute of MIT and Harvard notes, “Working with the tumor DNA of golden retrievers, cocker spaniels and boxers, we have identified genes with known involvement in human lymphoma and other cancers as well as novel genes that could help in the discovery of much-needed new treatment options for cancer.”
Dogs are becoming increasingly invaluable in cancer studies to understand the similarities of the disease in both human and dogs. Hopefully, the findings from these studies will yield results that can be applied to novel approaches to treat and cure cancer. To read the publication in Genome Research, please click here.