Animal Research Provides New Insight into Congenital Heart Defects

Findings published in the international journal Human Molecular Genetics shed new light into the causes of congenital heart defects associated with a rare developmental disorder.  Cornelia de Lange Syndrome (CdLS) can occur in up to 1 in 10,000 births globally and approximately 70% of those with CdLS will have congenital heart defects, according to an article posted on HealthCanal.com.  Animal research, specifically with zebrafish, is giving scientists more information on heart defects in people with CdLS.

Researchers at the University of Otago in New Zealand found that zebrafish embryos developed almost normally when a specific protein was partially depleted but these embryos exhibited the presence of heart structural abnormalities.

To learn more about CdLS and this discovery, please read the article by clicking here.